UC researchers looking for trial participants in knee pain study

UC researchers looking for trial participants in knee pain study. (WKRC)

CINCINNATI (WKRC) - A breakthrough trial could help you overcome a real pain in the knee.

The trial at the University of Cincinnati is one of the first of its kind to use what's already in your own body to help it fight back.

It uses an injection therapy that, if it works, could offer a whole new option for beating and treating pain, without surgery or medication.

For more than a decade, Pat Chambers says she's had pain in both knees from osteoarthritis.

“The left knee has always been the worst,” said Chambers.

So now, in an effort to heal the pain and delay surgery, she's part of a breakthrough trial using her own body to fight back.

“I liked it because it's your own blood, no drugs involved,” said Chambers.

Here's how it works: Blood is drawn and then put into a spinner. It's then spun down twice to isolate two special molecules that block inflammatory pain.

It is a receptor antagonist, so it works against those molecules, and it basically tricks your knee into making you not sense the pain, associated with arthritis.

Pat is then given either the study injection or her own blood, and followed for the next year to study everything from better function to less pain.

“We’ll be able to really figure out if we are attacking arthritis at its root, meaning are we eliminating the inflammatory pain associated with arthritis,” said Dr. Brian Grawe.

Grawe says what makes this one-of-a-kind therapy unique is that it takes a unique approach.

“We're treating knee as an organ, meaning your knee is made up of multiple parts of tissue, bone, cartilage, synovium, which is the lining of the joint, and by attacking it with a biologic solution, hopefully we can prevent the disease progression and ultimately eliminate the need for knee replacement,” said Grawe.

“I'm hoping for pain relief to put off my impending total knee I’m told I will need down the road,” said Chambers.

This study is open to anyone age 18 and up.

The number to call is 513-584-3931. You can leave a message, but you can reach a person if you call during business hours.

If you qualify for the study, there is no cost to you. They do an MRI and you are paid for time and travel.


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