Sean McNeil scored 17 points, Justice Sueing added 16 and 13th-seeded Ohio State held on to defeat 12th-seeded Wisconsin.
Two-year starter C.J. Stroud is off to the NFL in the draft next month, which means Ohio State coach Ryan Day needs to find a new quarterback.
A.J. Hoggard scored 15 of his 23 points in the second half and Michigan State finished the regular season with an 84-78 win over Ohio State.
Felix Okpara had 12 points and 12 rebounds as six players reached double figures for the Buckeyes
Kris Murray scored 26 points, Tony Perkins flirted with the first triple-double in Iowa history and the Hawkeyes beat No. 15 Indiana.
Bruce Thornton scored 20 points, fellow freshman Brice Sensabaugh scored 14 and senior Justice Sueing contributed a double-double in Buckeyes victory.
Buckeyes fall to 11-17 overall and 3-14 n the Big Ten Conference.
Brice Sensabaugh led the Buckeyes (11-16, 3-13) with 20 points. Sean McNeil added 10 points for Ohio State, which lost its eighth consecutive game.